Broccoli Sprout Extract for Cognitive Function

Exclusion Criteria

• •Severe medical conditions within the past 6 months: History of severe cerebrovascular disease (cerebral infarction, cerebral hemorrhage), cardiac disease (angina, myocardial infarction, heart failure, arrhythmia requiring treatment), or malignancy (Note: Participants with a history of cerebrovascular or cardiac disease who are clinically stable may be included at the investigator's discretion)
• •Cognitive impairment-associated diseases: Dementia, Parkinson's disease, cerebral infarction, or other conditions associated with cognitive decline Uncontrolled hypertension: Blood pressure ≥160/100 mmHg (measured after 10 minutes of rest)
• •Poor glycemic control: Fasting blood glucose ≥160 mg/dL in diabetic patients
• •Uncontrolled thyroid dysfunction: Currently receiving treatment for uncontrolled hypothyroidism or hyperthyroidism
• •Renal impairment: Serum creatinine ≥2 times the upper limit of normal for the institution
• •Hepatic impairment: AST or ALT ≥2 times the upper limit of normal for the institution
• •Severe gastrointestinal symptoms: Complaints of severe heartburn, dyspepsia, or other gastrointestinal distress
• •Medications affecting cognitive function within the past month: Use of drugs (antipsychotics, anti-degenerative agents, cognitive enhancers, tricyclic antidepressants, hormone replacement therapy) or health functional foods that may influence cognitive function due to dementia or other cognitive abnormalities
• •Other clinical trial participation: Participation in other drug clinical trials within the past month or planned participation during the study period
• •Alcohol use disorder, severe
• •Food allergies: Known allergic reactions to study product components
• •Investigator discretion: Any other condition deemed inappropriate for study participation by the investigator