Age

18–45

Sex

MALE

Healthy volunteers

Not accepted

Biological male, age 18 to 45 years inclusive
Molecular genetic confirmation of the full Fragile X messenger ribonucleoprotein mutation (≥200 CGG repetitions)
IAAS symptoms leading to a CGI-S score for Disruptive Behavior of 5 or more
Reported history of aggression based on the CMAI-Agg subscale (average score \>22) and an average associated disruptiveness scale of at least 3.
IQ \< 70
Stable medication doses for the last month
Has a caregiver who lives with or spends extensive time with the participant most days and can report behavioral symptoms
Must be able to swallow study drug capsules whole

Inhibition of Aggressive Behavior in Participants With Fragile X Syndrome