Evaluating Whether Intact Fish Skin Graft Can Decrease the Need for Autograft in the Treatment of Deep Partial-Thickness Burns

Inclusion Criteria

• •1. At least 18 years of age at time of consent
• •2. Must have thermal burn(s) with intact dermal elements for which excision and autografting are clinically indicated.
• •3. Be able to provide written informed consent or have a legally authorized representative
• •4. Have sufficient healthy skin identified and designated as a potential donor site in the event that the IFSG treatment site requires autografting.
• •5. Investigator expects that the donor site will heal without grafting
• •6. Have a complex skin defect of 3 to 49% Total Body Surface Area, which can consist of more than one contiguous area
• •At the time of debridement:
• •7. Have thermal burn(s) with intact dermal elements for which excision and autografting are clinically indicated
• •8. Study treatment areas can be up to 2000 cm2
• •9. Must have at least 100 cm2 TBSA for which autografting is indicated and on which IFSG can be applied, which may be composed of up to 3 non-contiguous areas located on the same extremity or plane of the torso
• •10. Application of IFSG or SOC must be initiated within 14 days of injury (Application of IFSG or SOC must be initiated within 14 days of injury)
• •11. Have first excision and grafting of study treatment sites
• •12. Have thermal burn(s) on the torso or extremities