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HUD Surgical Guidance for Toric Alignment | Clinical Trials | Clareo Health

RECRUITINGNA

HUD Surgical Guidance for Toric Alignment

Clinical Evaluation of a Novel Intraoperative Guidance System for Accurate Toric IOL Positioning in Cataract Surgery

NCT07325188•Gainesville Eye Associates

Summary

This study aims to assess the accuracy of toric intraocular lens (IOL) alignment axes as calculated and displayed by a novel digital guidance system. In addition, it evaluates the time required to initiate surgical guidance and postoperative refractive astigmatism following toric IOL implantation. This single-surgeon, single-site, prospective, non-invasive observational study evaluated the accuracy of toric IOL alignment axes calculated and displayed by the digital guidance system (Cassini Technologies, B.V.) in 100 eyes. The intraoperatively calculated alignment axes were compared to preoperative measurements to assess their accuracy (in degrees). Postoperative outcomes, including residual refractive astigmatism (diopters) and visual acuity (Snellen), were recorded at 1 month postoperatively.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Patients undergoing uncomplicated cataract surgery with toric IOL implantation,
•Eyes implanted with a toric IOL.

Exclusion Criteria

•Ocular comorbidity likely to impair postoperative visual acuities, or
•History of ocular trauma or zonular instability, or
•Previous refractive surgery, or
•Irregular corneal astigmatism or keratoconus, or
•Patients with physical or intellectual disabilities that may prevent reliable fixation or comprehension (e.g. Down's Syndrome, Parkinson's Disease), or
•Patients with unreliable biometry measurements, or
•Severe dry eye disease or ocular surface disease.

Locations (1)

North Georgia Eye Associates

Gainesville, Georgia, United States

Key Dates

Start Date

November 4, 2025

Primary Completion Date

October 1, 2026

Completion Date

October 31, 2026

Last Updated

January 8, 2026

Enrollment

100

ESTIMATED participants

Conditions

Cataract and IOL Surgery

Interventions

Cassini Guidance

DEVICE

Contacts

Dr. Clayton Blehm Blehm, MD

CONTACT

(770) 532-4444 claytonblehm@gmail.com

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ENROLLING_BY_INVITATIONNA

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 8, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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HUD Surgical Guidance for Toric Alignment

Inclusion Criteria

Exclusion Criteria

Head-to-Head Comparison of Five Enhanced Depth of Focus IOLs and One Monofocal IOL

Effectiveness of a Large Language Model-Based Educational Tool on Intraocular Lens Options

The Impact of Physiologic Cataract Surgery on Patient Comfort and Medication Usage

Comparing Visual Outcomes in Matched Patients Receiving a Low Cylinder Power Toric IOL or a Non-toric IOL