Clinical Study on the Safety and Efficacy of Tendon Stem Progenitor Cells Therapy for Rotator Cuff Tears

Exclusion Criteria

• •1. Tear size classified as large (3 cm to 5 cm) or massive (\> 5 cm) according to the DeOrio and Cofield classification, or Patte grade 3 tendon retraction;
• •2. Subscapularis tendon tear;
• •3. Complicated with anterior, posterior, or multidirectional shoulder joint instability;
• •4. Indications for repair of anterior or posterior labral injury;
• •5. Intra-articular injection of hyaluronic acid or corticosteroids within 3 months prior to the planned surgery;
• •6. Comorbidities that contraindicate arthroscopic shoulder surgery;
• •7. Local (shoulder, abdomen, buttocks) or systemic infection, osteomyelitis, or sepsis;
• •8. Diabetes mellitus, untreated thyroid disease, chronic kidney disease, or rheumatoid arthritis;
• •9. Immunodeficiency;
• •10. Chronic diseases involving coagulation or platelet aggregation, or severe coagulopathy;
• •11. Severe cardiovascular disease;
• •12. Stroke or acute cardiovascular event within 6 months prior to the planned surgery;
• •13. Weight loss \> 30 kg for any reason within 12 months, or unexplained weight loss \> 10 kg within 12 months;
• •14. Eating disorder or body dysmorphic disorder;
• •15. Alcohol/drug addiction or mental illness that may affect compliance with postoperative protocols;
• •16. Pregnant or lactating women;
• •17. Refusal to sign the informed consent form;
• •18. Other conditions deemed inappropriate by the investigators.