Clinical Study on the Treatment of Rhinitis Sicca With Sodium Hyaluronate Adjustable Nasal Irrigator

NCT07308015•China-Japan Union Hospital

Summary

To observe the therapeutic effect of sodium hyaluronate adjustable nasal irrigator on various types of rhinitis sicca and compare it with the therapeutic effect of the commonly used physiological seawater nasal spray in clinical practice.

Eligibility

Age

18 - 75 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Symptoms: Dry nose sensation, little and thick nasal discharge, nosebleeds, itchy nasal cavity, and dryness in the nasopharynx. Physical signs: Nasal endoscopy often reveals dry and congested nasal mucosa, which appears grayish-white or dark red, losing its normal luster. There are often dry, thick secretions, scabs or blood scabs on it. The surface of the nasal mucosa is eroded and ulcers occur. The mucosal lesions are most obvious in the anterior part of the nasal cavity. A diagnosis can be made if one or more of the above symptoms and signs are present.

Exclusion Criteria

•1. Those with dry rhinitis and chronic inflammation of the lower respiratory tract.
•2. Those confirmed by examination to be caused by certain latent lesions in the mouth, nose, throat, esophagu.s, neck or the whole body
•3. Those who have used drugs for treating dry rhinitis or other medications within the past 30 days.
•4. Pregnant or lactating women.
•5. Those who are allergic to this medicine.
•6. Those with severe cardiovascular, liver, kidney and hematopoietic system diseases, etc.
•7. Mentally ill patients.

Locations (1)

China-Japan Union Hospital of Jilin University

Changchun, Jilin, China

Key Dates

Start Date

June 16, 2025

Primary Completion Date

June 12, 2026

Completion Date

June 12, 2026

Last Updated

December 29, 2025

Enrollment

200

ESTIMATED participants

Conditions

Rhinitis Sicca

Interventions

Physiological seawater adjustable nasal irrigator

DRUG

Sodium hyaluronate adjustable nasal irrigator

DRUG

Contacts

Cuida Meng, Doctor

CONTACT

86+13596096000 mengcd@jlu.edu.cn

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: December 29, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

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