Blind Versus Targeted Epidural Patch With Autologous Platelet-rich Plasma for Spontaneous Intracranial Hypotension

Exclusion Criteria

• •1. There was concern for other causes of intracranial hypotension, such as postdural puncture, postsurgical and post-traumatic CSF leaks.
• •2. Prior treatment with EBP at any time previously.
• •3. Any contraindication to epidural puncture, such as space-occupying intracranial or intraspinal lesions, spinal defect, suspected infection over the puncture site, bleeding disorder and current anticoagulation therapy.
• •History of drug and alcohol abuse, cognitive dysfunction, or mental illness.
• •4. Unable to comprehend the pain NRS.
• •5. Unable to cooperate with postoperative treatment, rehabilitation, and follow-up visits.