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Effect of Stellate Ganglion Block on Postoperative Sleep Status in Patients With Prolonged Disorders of Consciousness: a Single--Centre Cohort Study
The goal of this clinical trial is to learn about the effect of preoperative administration of stellate ganglion block on postoperative sleep status in patients with prolonged disorders of consciousness. The main aims to answer are: • To explore the effect of preoperative administration of stellate ganglion block on postoperative polysomnography and total sleep time in patients with prolonged disorders of consciousness. • To explore the effect of preoperative administration of stellate ganglion block on postoperative cerebral oxygen saturation, cerebral hemodynamic parameters and recovery of consciousness. Participants will be pDoC patients with intact skulls after acquired brain injury who will undergo spinal cord electronic stimulator implantation under general anesthesia at Beijing Tiantan Hospital. Stellate ganglion block will be administrated before the surgery. Polysomnography, total sleep time, cerebral oxygen saturation, cerebral hemodynamic parameters, CRS-R scores, GCS scores, WHIM scores and NCS scores will be investigated.
Age
18 - 65 years
Sex
ALL
Healthy Volunteers
No
Beijing Tian Tan Hospital
Beijing, China
Start Date
January 1, 2026
Primary Completion Date
July 1, 2026
Completion Date
January 1, 2027
Last Updated
December 10, 2025
25
ESTIMATED participants
stellate ganglion block with 0.5% ropivacaine
DRUG
Lead Sponsor
Beijing Tiantan Hospital
NCT06430957
NCT01778504
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