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A Randomized Ablation-based Atrial Fibrillation Rhythm Control Versus Rate Control Trial in Patients With Heart Failure and Preserved Ejection Fraction (CABANA-RAFT HF): A Pilot Study
This study is testing two different ways of treating atrial fibrillation (AF) in people who also have heart failure with mildly reduced or preserved heart function. Patients will randomly be assigned to either rhythm control using catheter ablation or rate control using medicines. The pilot phase will determine if a larger study can be successfully carried out to see which approach better improves survival, reduces hospitalizations, and enhances quality of life.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
QEII HSC
Halifax, Nova Scotia, Canada
Start Date
January 1, 2026
Primary Completion Date
October 1, 2027
Completion Date
October 1, 2027
Last Updated
February 17, 2026
84
ESTIMATED participants
Catheter Ablation for Atrial Fibrillation
PROCEDURE
Rate Control Medications (beta-blockers, calcium channel blockers, digoxin)
DRUG
Lead Sponsor
Nova Scotia Health Authority
Collaborators
NCT06935591
NCT07219511
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and ConditionsNCT07430007