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The Impact of BBTI on Cognition and Sleep Health in Older Adults With HIV
The goal of this clinical trial is to examine the effects of a telephone-delivered Brief Behavioral Treatment Insomnia (BBTI) versus a Brief Mindfulness Treatment (BMT) on cognitive and sleep outcomes in older adults with HIV. The main questions it aims to answer are: What are the effects of BBTI vs BMT on self-reported and observed sleep outcomes in older adults with HIV and insomnia up to 1-year post-intervention? What are the effects of BBTI vs BMT on self-reported and observed cognitive comes in older adults with HIV and insomnia up to 1-year post-intervention? What is the association between Alzheimer's Disease biomarkers and sleep and cognitive outcomes in older adults with HIV receiving BBTI vs BMT? Participants will: * Complete 4 weeks of telephone-delivered BBTI or BMT * Attend baseline, post-intervention, and 1-year post in-person visits for sleep and cognitive assessments * Have blood collected at all three time points
Age
50 - 99 years
Sex
ALL
Healthy Volunteers
No
The University of Alabama at Birmingham
Birmingham, Alabama, United States
The University of Alabama
Tuscaloosa, Alabama, United States
Start Date
January 1, 2026
Primary Completion Date
September 1, 2030
Completion Date
September 1, 2030
Last Updated
January 29, 2026
214
ESTIMATED participants
BBTI
BEHAVIORAL
BMT
BEHAVIORAL
Lead Sponsor
University of Alabama, Tuscaloosa
Collaborators
NCT06032377
NCT06807086
NCT06181643
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
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