Patients with one or more lesions amendable to undergo EUS-RFA
* Insulinomas ≤ 25 mm confirmed by a 72-h fasting test, cross-sectional scanning, and a biopsy with low Ki67 index (\<10%)
* Non-functional pNEN lesions between 10-20 mm and growing, confirmed by a biopsy with low Ki67 index (\<10%), or larger pNEN lesions in patients who are not candidates for surgical treatment
* Unilateral APA with benign characteristics on non-contrast enhanced CT located in the left adrenal and confirmed lateralization on AVS
* Adult habile patients
* Signed informed consent
You may not be if
Severe multimorbidity (ASA score ≥ IV or ECOG performance score ≥ 4)
