2. On maximally tolerated ACEi or ARB per principal investigator discretion within 1 month of informed consent.
3. Estimated glomerular filtration rate ≥25 milliliters per minute per 1.73 square meters by Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation.
4. Kidney biopsy collected within 5 years of screening consistent with FSGS or kidney biopsy collected ≥5 years prior to screening consistent with FSGS plus the presence of a pathogenic gene mutation known to be associated with FSGS.
You may not be if
1. Collapsing FSGS in the kidney biopsy report.
2. Sickle cell disease.
3. HbA1c \>8%.
4. Uncontrolled hypertension (≥160/100 millimeters of mercury).
Clareo Health | A Study of Praliciguat in Participants With Focal Segmental Glomerulosclerosis (FSGS)
