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Not Yet RecruitingPhase 4NCT07265128

Remimazolam vs Midazolam to Reduce Delirium in Adults ≥65 Undergoing CPB Valve Surgery

"Postoperative delirium is a common and serious complication following cardiac surgery, particularly among older adults who require intensive care. Its incidence is reported to range between 20% and 7...

Lead sponsor: Yonsei University•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Yonsei University

Age

65 - 99 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Patients aged 65 years or older undergoing heart valve surgery involving cardiopulmonary bypass.

Exclusion Criteria

•Emergency surgery, Surgery involving total arch replacement, History of remimazolam anaphylaxis, History of major neurocognitive disorder, Alcohol or substance dependence/abuse, Major depressive disorder, Schizophrenia, Participation in other clinical studies that may affect outcomes, Inability to provide informed consent due to illiteracy, foreign language barrier, or cognitive impairment.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: December 4, 2025Terms

Trial snapshot

StatusNOT_YET_RECRUITING

PhasePHASE4

Enrollment300

Start dateDec 2025

Last updatedDec 4, 2025

Condition

Delirium Critical Illness Aged Cardiopulmonary Bypass Benzodiazepines

Locations shown

Department of Anaesthesiology and Pain Medicine, Yonsei University College of Medicine

Seoul

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: December 4, 2025Data synced to Clareo: May 3, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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