Observational Study of Gut Microbiota in Abemaciclib-Treated Patients With and Without Diarrhea

Exclusion Criteria

• •1. History of major gastrointestinal diseases, such as inflammatory bowel disease, Crohn's disease, ulcerative colitis, or intestinal obstruction, or having undergone major gastrointestinal surgery.
• •2. Recent use (within 1 month) of antibiotics, probiotics, or traditional Chinese medicine that may alter gut function.
• •3. Pregnant or lactating women.
• •4. Unwilling to provide informed consent or considered by the investigator to be unsuitable for the study for any other reason.