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Dexmedetomidine as an Adjuvant to Bupivacaine for Ultrasound-Guided External Oblique Intercostal Block | Clinical Trials | Clareo Health

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Dexmedetomidine as an Adjuvant to Bupivacaine for Ultrasound-Guided External Oblique Intercostal Block

Effect of Adding Dexmedetomidine as Adjuvant to Bupivacaine in Ultrasound Guided External Oblique Intercostal Plane Block in Upper Abdominal Cancer Surgery. A Prospective Randomized Clinical Trial

NCT07263165•Assiut University

View on ClinicalTrials.gov

Summary

Effect of Adding Dexmedetomidine as Adjuvant toBupivacaine in Ultrasound Guided ExternalOblique Intercostal Plane Block in UpperAbdominal Cancer Surgery.

Detailed Description

Effect of Adding Dexmedetomidine as Adjuvant toBupivacaine in Ultrasound Guided ExternalOblique Intercostal Plane Block in UpperAbdominal Cancer Surgery. A prospectiverandomized clinical trial

Eligibility

Age

18 - 70 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Patients aged 18-70 years scheduled for elective upper abdominal cancer surgery (e.g., gastrectomy, hepatectomy, pancreatectomy).
•American Society of Anesthesiologists (ASA) physical status I-III.
•Body mass index (BMI) between 18-35 kg/m².

Exclusion Criteria

•Patient refusal.
•Allergy to local anesthetics or dexmedetomidine.
•Coagulopathy (INR \>1.5, platelet count \<100,000/mm³).
•Infection at the injection site.
•Severe cardiopulmonary, renal, or hepatic dysfunction.
•Chronic opioid use (\>30 mg morphine equivalents daily for \>3 months).
•Pregnancy or lactation.

Key Dates

Start Date

December 15, 2025

Primary Completion Date

February 15, 2026

Completion Date

December 15, 2027

Last Updated

December 4, 2025

Enrollment

ESTIMATED participants

Conditions

Opioid Consumption, Postoperative

Interventions

Dexmedetomidine

DRUG

Contacts

Mohamed i Shaker

CONTACT

01012248619 aboiprahem1997@gmail.com

Moaaz M Tohamy

CONTACT

moaaz@aun.edu.eg

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: December 4, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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