Efficacy of Solventum™ Vitrebond™ Pulp Protect Liner/Base Used as a Liner/Base Under Dental Restorations

Exclusion Criteria

• •1. Subject has a history of adverse reaction to any materials used in this study, including but not limited to acrylates.
• •2. Subject is unable, for any reason, to tolerate the study procedures or the length of time required to complete the restoration(s) on the study tooth.
• •3. Subject is taking part in or planning to be enrolled in a clinical evaluation of any other dental materials at any time during the study.
• •4. Subject has a history of chronic use of anti-inflammatory, analgesic (pain), and/or mind-altering drugs for medical (including psychiatric) and pharmacotherapeutic therapies that might alter perception of pain.
• •5. Subject is pregnant or breast feeding at the time of screening.
• •6. Subject has any spontaneous or other orofacial pain (including toothache, percussion tenderness, and periapical radiolucency).
• •7. Subject has caries or conditions involving non-study teeth that may interfere with the sensitivity assessments (e.g., advanced caries in a non-study tooth in the same quadrant as the study tooth).
• •8. Subject has Temporal Mandibular Disorder with pain.
• •9. Study tooth with current or previous trauma or previous restorations.
• •10. Study tooth diagnosed with cracked tooth syndrome.
• •11. Study tooth with mobility \>= grade 2 using the Miller's tooth mobility index.
• •12. Study tooth has previous and/or current signs or symptoms of pulpal and/or periapical disease (e.g., root resorption or pulpal calcifications) or irreversible pulpitis.
• •13. Tooth surface loss (attrition, erosion, abrasion or abfraction) on study tooth or adjacent teeth that could impact perception of pain.
• •14. Study tooth has no systemic mineralization pathology (e.g., amelogenesis imperfecta, enamel hypoplasia, etc).
• •16. Study tooth with pulp exposure under any circumstance (caries exposure, mechanical/traumatic).