Clareo Health | Effect of Probiotic Supplementation on Renal Function, Vascular Calcification and Alterations in Bone Mineral Metabolism in Patients With Chronic Kidney Disease
Effect of Probiotic Supplementation on Renal Function, Vascular Calcification and Alterations in Bone Mineral Metabolism in Patients With Chronic Kidney Disease
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Keep this study
Lead
Maimónides Biomedical Research Institute of Córdoba
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. Be of legal age (≥18 years).
2. Patients with stage 5 CKD in pre-dialysis or dialysis with evidence of cardiovascular disease. Calcification will be quantified using the Kaupilla and Adragao indices as indicated in Appendix 1. All radiographs necessary to assess the degree of calcification (both at the beginning and end of the study) will be examined by the same radiologist. To avoid bias in the assessments, the calculation of the Adragao and Kaupilla indices will be performed by staff from the Radiology Department of the Reina Sofía University Hospital.
3. Negative pregnancy test.
4. Patient capable of understanding the study procedures and who provides informed consent to participate in the research project.
You may not be if
1 Patients diagnosed with or suspected of having inflammatory bowel disease.
2\. Patients undergoing antibiotic treatment within the last two months prior to the start of the study.
3\. Patients with recurrent infections or diverticula treated intermittently with antibiotics.
4\. No cardiovascular history.
5\. Other cardiovascular or metabolic disorders.
6\. Pregnant or breastfeeding women, or women planning to become pregnant.
7\. Drug or alcohol addiction that, in the investigator's opinion, could interfere with compliance with the study requirements.
8\. Participation in other clinical studies.
9\. Incapacity or unwillingness of the individual, legal guardian, or representative to provide written informed consent.
