Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of California, Davis
With
National Cancer Institute (NCI)
PRIMARY OBJECTIVE:
I. To compare the efficacy of PRAME IHC-guided slow Mohs micrographic surgery to routine slow Mohs micrographic surgical practices in patients with melanoma.
SECONDARY OBJECTIVE:
I. To further evaluate the efficacy of PRAME IHC-guided slow Mohs micrographic surgical practices in patients with melanoma.
OUTLINE:
Patients undergo standard slow Mohs micrographic surgery with the addition of PRAME IHC analysis per the discretion of the surgeon on study.
After completion of study treatment, patients are followed up every 6 months for up to 5 years.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Scheduled for SMMS of cutaneous melanoma (stage 0 through stage IIc per American Joint Committee on Cancer \[AJCC\] criteria)
Age \>= 18 years at time of consent
Initial tumor biopsy is PRAME positive or PRAME testing was not done. PRAME testing must be planned if not done
Provision of signed and dated informed consent form
Stated willingness to comply with all study procedures and availability for the duration of the study
You may not be if
Initial biopsy was PRAME negative
Incarcerated persons
Patient with severe, active co-morbidity that would preclude a SMMS of cutaneous melanoma (stage 0 through stage IIc per AJCC criteria)
