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Balanced Progressive Intensity Training (BPIT): A Five-Week Multi-Site Clinical Evaluation of Functional Movement, Mobility, and Neuromuscular Adaptation in Healthy Adults (18-65 Years)
This prospective, multi-site, single-arm interventional study evaluates the 5-Line Principle of Balanced Progressive Intensity Training (BPIT) over 5 weeks in healthy adults aged 18-65 years. All participants receive supervised BPIT sessions (3-5 per week) progressing through five intensity lines defined by anatomical landmarks and ground reaction force: Ground-Based (Low) Knee-Level (Low-Moderate) Standing (Moderate) Head-Level (Moderate-High) Plyometric (High-Impact) The study aims to quantify improvements in functional movement efficiency, joint mobility, postural control, strength adaptation, and heart-rate variability while monitoring safety and individual overload indicators.
Primary Outcome Measures Change in Functional Movement Screen (FMS) total score from baseline to Week 5 Change in Y-Balance Test reach distance (composite score) Timeframe: Baseline and Week 5 Secondary Outcome Measures Change in 1-RM or estimated strength (squat, deadlift, overhead press) Change in resting HRV (RMSSD) Change in joint range of motion (goniometry) and postural sway Incidence of training-related discomfort or minor injury Timeframe: Baseline, weekly, and Week 5 Arms/Intervention Experimental: BPIT 5-Line Training Group Intervention: Behavioral: Balanced Progressive Intensity Training (BPIT) 5-Line Method Description: 5-week supervised progressive training using the BPIT 5-Line framework (ground-based → plyometric) Eligibility Ages Eligible: 18 Years to 65 Years Sexes Eligible: All Accepts Healthy Volunteers: Yes Inclusion Criteria Healthy adults with regular exercise history Able to attend 3-5 training sessions/week Signed informed consent Exclusion Criteria Recent injury (\<3 months) Known cardiovascular, metabolic, or orthopaedic contraindications Pregnancy Study Locations 13 Locations in India 2 Locations in USA, (Details of the location is uploaded on mmsxauthority.com webiste) MMSx Authority , USA, GFFI Fitness Academy, New Delhi BodyGNTX USA BFS/AIHFT-approved facilities Countries of Recruitment India U.S. FDA-regulated? No / No / No Human Subjects Protection Review Board Status Approved (or Submit for review if not yet) Board Name: Institutional Ethics Committee - MMSx Authority / GFFI Approval Number: BPIT-MULTI-2025-001 (or pending) Data Monitoring Committee No
Age
18 - 65 years
Sex
ALL
Healthy Volunteers
Yes
BodyGNTX Fitness Institute
Columbus, Ohio, United States
MMSx Authority Biomechanics Department
Powell, Ohio, United States
MMSx AUTHORITY INSTITUTE FOR MOVEMENT MECHANICS & BIOMECHANICS RESEARCH (COORDINATING CENTER)
Powell, Ohio, United States
Indian Institute of Kinesiology & Biomechanics Science (IIKBS)
Burhānpur, Madhya Pradesh, India
Shri Mahaveer Ortho Clinic
Delhi, National Capital Territory of Delhi, India
GFFI Fitness Academy
New Delhi, National Capital Territory of Delhi, India
Active India Health & Fitness Trust (AIHFT)
New Delhi, National Capital Territory of Delhi, India
Body Mechanics Gym P Ltd
New Delhi, National Capital Territory of Delhi, India
Regain Fitness Zone
Greater Noida, Uttar Pardesh, India
GFFI Fitness Academy
Agra, Uttar Pradesh, India
Start Date
October 10, 2025
Primary Completion Date
February 15, 2026
Completion Date
February 25, 2026
Last Updated
December 16, 2025
369
ESTIMATED participants
Balanced Progressive Intensity Training (BPIT) 5-Line Method
BEHAVIORAL
Lead Sponsor
MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc.
Collaborators
NCT06212856
NCT06590103
Data Source & Attribution
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