Patients for whom at least one of the following conditions has been confirmed:
Systemic lupus erythematosus meeting the 2019 ACR/EULAR classification criteria.
Systemic scleroderma meeting the 2013 ACR/EULAR classification criteria. ANCA-associated vasculitis according to the 2022 EULAR/ACR classification criteria.
Antiphospholipid syndrome according to the 2023 ACR/EULAR criteria.
Primary immunodeficiencies according to IUIS criteria.
Patients capable of understanding the objectives of the research.
Patients affiliated with a social security health insurance scheme (beneficiary or dependant).
Patients who have signed and dated the informed consent form for non-identifying genetic testing.
You may not be if
Patient refusing to participate in the study
Patient in a period of exclusion (determined by a previous or ongoing study) Inability to provide the subject with informed consent (in an emergency or immediate life-threatening situation, difficulties in understanding the subject, etc.)
