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Comparison Between Effect of Empirical Antibiotic Prophylaxis Versus Enhanced Prophylactic Measures on Rate of Urinary Tract Infection After Flexible Ureteroscopy in Children With Pyuria | Clinical Trials | Clareo Health

COMPLETEDPHASE2/PHASE3

Comparison Between Effect of Empirical Antibiotic Prophylaxis Versus Enhanced Prophylactic Measures on Rate of Urinary Tract Infection After Flexible Ureteroscopy in Children With Pyuria

NCT07229755•Ain Shams University

View on ClinicalTrials.gov

Summary

The aim of this study is to compare between effect of empirical antibiotic prophylaxis versus enhanced prophylactic measures on rate of urinary tract infection after Flexible ureteroscopy in Children.

Eligibility

Age

4 - 14 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Age starting from 4 up to 14 years old.
•Patients with renal stones from 1cm to 1.5cm in largest dimensions (not more than 4 cm3 measured by CTUT) undergoing flexible URS.

Exclusion Criteria

•Patients who refuse to participate in the study.
•Patients with single functioning kidney.
•Patients with rising serum creatinine.
•Known patient with neurogenic bladder.
•Patients with DM type1.
•Immunocompromised children.
•* Children with coagulopathy.
•* Patients with untreated UTI (or any interfering symptoms with UTI as fever or irritative LUTS).

Locations (1)

Ain Shams University

Cairo, Egypt

Key Dates

Start Date

July 1, 2024

Primary Completion Date

December 31, 2024

Completion Date

February 5, 2025

Last Updated

November 17, 2025

Enrollment

140

ACTUAL participants

Conditions

Urinary Tract Infection (Diagnosis)

Interventions

Ceftriaxone (Rocephin®)

DRUG

Levofloxacin

DEVICE

Intravesical Lactobacillus Crispatus: Clinical Safety and Microbiome Evaluation

NCT07308808

Spinal Cord Injuries (SCI)Neurogenic Bladder+1 more

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RECRUITINGNA

Is Methenamine Prophylaxis for Urinary Tract Infection After Midurethral Sling as Effective as Antibiotic Prophylaxis?

NCT06810687

Urinary Tract Infection (Diagnosis)

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: November 17, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Comparison Between Effect of Empirical Antibiotic Prophylaxis Versus Enhanced Prophylactic Measures on Rate of Urinary Tract Infection After Flexible Ureteroscopy in Children With Pyuria

Inclusion Criteria

Exclusion Criteria

Intravesical Lactobacillus Crispatus: Clinical Safety and Microbiome Evaluation

Is Methenamine Prophylaxis for Urinary Tract Infection After Midurethral Sling as Effective as Antibiotic Prophylaxis?

Efficacy of Collagen, Propolis Plus Quercetin (Proqutin®), Bacillus Coagulans, Hyaluronic Acid and Chondroitin Sulphate and D-Mannose to Avoid Symptoms and Prevents Recurrence in Women With Recurrent Urinary Tract Infections

Extending Urine Analysis By Direct Mass Spectrometry