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Efficacy of Collagen, Propolis Plus Quercetin (Proqutin®), Bacillus Coagulans, Hyaluronic Acid and Chondroitin Sulphate and D-Mannose to Avoid Symptoms and Prevents Recurrence in Women With Recurrent Urinary Tract Infections | Clinical Trials | Clareo Health

COMPLETEDPHASE4

Efficacy of Collagen, Propolis Plus Quercetin (Proqutin®), Bacillus Coagulans, Hyaluronic Acid and Chondroitin Sulphate and D-Mannose to Avoid Symptoms and Prevents Recurrence in Women With Recurrent Urinary Tract Infections

EFFICACIA DI UN INTEGRATORE A BASE DI D-MANNOSIO, PROPOLI, QUERCETINA, COLLAGENE E BACILLUS COAGULANS NEL RIDURRE L'INCIDENZA E MIGLIORARE LA QUALITA' DI VITA IN DONNE CON CISTITE RICORRENTE

NCT06659016•University of Campania Luigi Vanvitelli

View on ClinicalTrials.gov

Summary

The aim of this study is to evaluate whether a dietary supplement based on D-mannose, collagen, hyaluronic acid, chondroitin sulphate, enhanced by the properties of quercetin plus propolis (Proqutin ®) and Bacillus Coagulans, eventually associated with antimicrobial prophylaxis, could be effective in preventing recurrent UTIs and improving related quality of life.

Eligibility

Age

21 - 65 years

Sex

FEMALE

Healthy Volunteers

Inclusion Criteria

•a history of rUTIs (defined by EAU guidelines as a frequency of at least three UTIs per year, or two UTIs in the past six months in the last 12 months, confirmed by positive urine cultures
•not undergone any previous treatment for their condition.

Exclusion Criteria

•age under or over limit
•concurrent antimicrobial treatment
•any ongoing treatment that could influence study outcomes,
•congenital or post-surgical urinary tract anomalies
•immunodeficiency or HIV infection
•ongoing pregnancy.

Locations (1)

University of Campania Luigi Vanvitelli

Naples, Italy

Key Dates

Start Date

February 1, 2023

Primary Completion Date

February 10, 2024

Completion Date

September 30, 2024

Last Updated

October 26, 2024

Enrollment

148

ACTUAL participants

Conditions

Urinary Tract Infection (Diagnosis)

Interventions

Fosfomycin 3 g

DRUG

Uroxin 4G

DIETARY_SUPPLEMENT

Combination of dietary supplement and fosfomycin

DRUG

Intravesical Lactobacillus Crispatus: Clinical Safety and Microbiome Evaluation

NCT07308808

Spinal Cord Injuries (SCI)Neurogenic Bladder+1 more

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RECRUITINGNA

Is Methenamine Prophylaxis for Urinary Tract Infection After Midurethral Sling as Effective as Antibiotic Prophylaxis?

NCT06810687

Urinary Tract Infection (Diagnosis)

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 26, 2024Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Efficacy of Collagen, Propolis Plus Quercetin (Proqutin®), Bacillus Coagulans, Hyaluronic Acid and Chondroitin Sulphate and D-Mannose to Avoid Symptoms and Prevents Recurrence in Women With Recurrent Urinary Tract Infections

Inclusion Criteria

Exclusion Criteria

Intravesical Lactobacillus Crispatus: Clinical Safety and Microbiome Evaluation

Is Methenamine Prophylaxis for Urinary Tract Infection After Midurethral Sling as Effective as Antibiotic Prophylaxis?

Comparison Between Effect of Empirical Antibiotic Prophylaxis Versus Enhanced Prophylactic Measures on Rate of Urinary Tract Infection After Flexible Ureteroscopy in Children With Pyuria

Extending Urine Analysis By Direct Mass Spectrometry