A Study of Avoralstat In Participants With Diabetic Macular Edema

Exclusion Criteria

• •1. Participants who have previously received more than 3 anti-VEGF injections
• •2. Any history of retinal surgery or other surgical intervention for diabetic ocular complications or anticipated need for use of laser photocoagulation course of any of the procedures listed in the criteria in the study eye during the study period
• •3. Current medically untreated diabetes mellitus or previous medically untreated diabetes mellitus with initiation of oral or injectable anti-diabetic medication ≤ 3 months prior to screening
• •4. Active intraocular or periocular infection or active intraocular inflammation in the study eye
• •5. Intraocular surgery ≤ 3 months prior to screening or anticipated need for ocular surgery in the study eye during the study period