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Not Yet RecruitingNANCT07228208

Role of Endothelial Dysfunction on Exercise Pressor Reflex in Type 2 Diabetes

Exaggerated blood pressure responses to exercise in individuals with Type 2 Diabetes significantly increase the risk of heart attack, stroke, and cardiovascular death, while also limiting exercise cap...

Lead sponsor: Medical College of Wisconsin•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Medical College of Wisconsin

Age

18 - 80 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Type 2 Diabetes: 18 - 80 years old, able to give informed consent, \> 6 months post-diagnosis, \> 6 months stable medications for management
•Healthy controls: 18 - 80 years old, able to give informed consent

Exclusion Criteria

•Type 2 Diabetes: Type 1 diabetes, symptomatic coronary artery disease, cardiovascular event in last year (MI, stroke), uncontrolled or unmanaged hypertension (\>160/90 mmHg), heart failure, renal impairments, current or recent (\<6 months) tobacco use, hormone replacement therapy, documented neuromuscular disorders, pregnancy
•Healthy Controls: Same as listed in Type 2 Diabetes with Type 2 Diabetes as an exclusion factor

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: November 14, 2025Terms

Trial snapshot

StatusNOT_YET_RECRUITING

PhaseNA

Enrollment40

Start dateSep 2026

Last updatedNov 14, 2025

Condition

Type 2 Diabetes (T2DM)Endothelial Dysfunction

Locations shown

Medical College of Wisconsin

Milwaukee, Wisconsin

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: November 14, 2025Data synced to Clareo: May 17, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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