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Keep this study
Lead
Applied Science & Performance Institute
Age
18–55
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Healthy males or females aged 18-55
Must be recreationally trained or trained/developmental as previously defined (McKay et al., 2021)
Able to read and write in English
You may not be if
Are not consistently taking, or will discontinue consuming other pre-workout supplements or dietary supplements, such as creatine, rhodiola, L-Theanine, glycerol, stimulants other than caffeine, or ingredients which may promote hydration or enhance physical performance within the past 2-weeks, and throughout the duration of the study.
Willing to restrict caffeine for 24 hours prior to testing
Will not participate in any strenuous exercise for a minimum of 72 hours prior to exercise performance assessments. Strenuous exercise as defined for this study includes ½ and full marathons (or more), heavy (i.e.,\>80% 1RM) lifting, and any high intensity, physical activity that could make your muscles sore.
Sedentary: Individuals performing less than 150 minutes of moderate or 75 minutes of vigorous activity per week and engaging in resistance training fewer than 2 days per week, with no structured exercise routine.
Highly trained/national level or professional athlete: Individuals training ≥5 days per week in structured programs, including NCAA Division II/III athletes, national/professional competitors, or those targeting top 20% sport-specific performance norms.
Known diagnosis of any cardiovascular, metabolic, endocrine, or renal disease
Recent musculoskeletal injury (\<3-months)
Recent orthopaedic surgery (\<12-months)
History or current malignancy
Previous gastrointestinal surgery within the past 12 months
Regular smoker
Regular drinker (\>14 drinks per week)
Current respiratory infection (i.e. cold) or high temperature (fever) within the past 4-weeks
Presently using GLP-1 medications
Individuals with cardiovascular, metabolic, or musculoskeletal disorders;
Those regularly using anti-inflammatory drugs within the last 4-weeks
Current use of prescription medications that may influence adaptation to exercise (hormone therapies, peptides, etc.)
Current consistent chronic use (within the past 2 weeks) of creatine, rhodiola, L-Theanine, glycerol, or other products which contain any of these ingredients.
Current consistent chronic use (within the past 2 weeks) of stimulants other than caffeine
Current consistent chronic use (within the past 2 weeks) of ingredients that may promote hydration or enhance physical performance.
Allergies to study-related materials
Any condition that may impair their ability to complete the required exercises (determined during screening).
Female subjects must not be pregnant or lactating
Are unable to provide informed consent or are non-English speakers.
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