Aspirin in Reducing Events in the Elderly-Extension (ASPREE-XT)

ASPREE-XT is a longitudinal, observational follow-on study of ASPREE participants. The methodology of ASPREE-XT is based closely on ASPREE \[ASPREE investigator group, 2013; www.aspree.org; McNeil et al. 2017\]. Clinical, neurocognitive and physical function measurements, questionnaires for mood, quality of life, physical ability and collection of personal health, demographic and lifestyle details are the same in ASPREE-XT as those conducted and described for ASPREE. Since ASPREE-XT is an observational study, the endpoints for ASPREE will be collected and adjudicated in a similar way for ASPREE-XT but will be referred to as ASPREE-XT Outcomes. These will not be divided into primary and secondary endpoints. In 2018, participants were invited to enroll in ASPREE-XT. At the first ASPREE-XT study visit, or via mail, they were provided with an information sheet and consent form for the study Participants who wish to only be contacted by phone were provided with information and a consent form by mail with health and other study data collected by phone call.