A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)

Inclusion Criteria

• •1. Male or female participants ≥12 years old on the day of signing informed consent/assent (Visit 1)
• •2. Weight of ≥40 kg at the screening visit (Visit 1)
• •3. Body mass index (BMI) of ≤40 kg/m² at the screening visit (Visit 1)
• •4. Participants with a diagnosis prior to the screening visit (Visit 1) of either:
• •* Biopsy-confirmed primary focal segmental glomerulosclerosis (pFSGS) (based on Investigator's judgement) OR
• •* Genetic focal segmental glomerulosclerosis (FSGS) resulting from a gain-of-function mutation in the transient receptor potential cation subfamily C member 6 (TRPC6) gene (based on historical genetic test)
• •5. Urine protein-creatinine ratio (UPCR) ≥1500 mg/g based on the mean of the spot urine sample and first morning void urine sample (both assessed by central laboratory) at the screening visit (Visit 1)
• •6. Estimated glomerular filtration rate (eGFR)
• •* For adult participants (≥18 years): ≥25 mL/min/1.73 m² (chronic kidney disease epidemiology collaboration (CKD-EPI) formula based on combined serum creatinine plus cystatin C) at the screening visit (Visit 1)