Radicle Clarity RPN: A Study Assessing the Impact of Health and Wellness Products on Cognitive Function and Related Health Outcomes.

Inclusion Criteria

• •\- Inclusion
• •Participants must meet all the following criteria:
• •Adults, at least 21 years of age at the time of electronic consent, inclusive of all ethnicities, races, and gender identities.
• •* Assigned sex at birth will determine sex-specific recruitment and surveys (male vs female) employed, when needed.
• •Resides in the United States.
• •Has the opportunity for at least 30% improvement in their primary health outcome.
• •Expresses a willingness to take a study product and not know the product identity (active or placebo) until the end of the study.
• •* Exclusion
• •Individuals who report any of the following during screening will be excluded from participation:
• •Report being pregnant, trying to become pregnant, or breastfeeding.
• •Unable to provide a valid US shipping address and mobile phone number.
• •Reports current enrollment in another clinical trial.
• •Reports being a heavy drinker (defined as drinking 3 or more alcoholic beverages per day).
• •Unable to read and understand English.
• •Reports a current and/or recent (up to 3 months ago) major illness and/or surgery that poses a known, significant safety risk.
• •Reports a diagnosis of cardiac dysfunction, liver or kidney disease that presents a known contraindication and/or a significant safety risk with any of the study product ingredients.
• •* NYHA Class III or IV congestive heart failure, atrial fibrillation, uncontrolled arrhythmias, cirrhosis, end-stage liver disease, stage 3b or 4 chronic kidney disease, or kidney failure.
• •Reports taking medications that have a well-established moderate or severe interaction, posing a substantial safety risk with any of the study product ingredients.
• •* Anticoagulants, antihypertensives, anxiolytics, antidepressants, chemotherapy, immunotherapy, sedative hypnotics, seizure medications, medications that warn against grapefruit consumption, corticosteroids at doses greater than 5 mg per day, diabetic medications, oral anti-infectives (antibiotics, antifungals, antivirals) to treat an acute infection, antipsychotics, MAOIs, or thyroid products.
• •Reports current use of the primary ingredient(s) and/or similar product(s) to the active study product(s) that may limit the effects of the study products.
• •Lack of reliable daily access to the internet.