REVascularization In Large VEssel Occlusion for Acute Ischemic Stroke

Exclusion Criteria

• •1. Any intracranial hemorrhage at baseline
• •2. Previous stroke within 90 days
• •3. Female who is pregnant or lactating or has a positive pregnancy test at time of admission
• •4. Arterial occlusive lesion is not technically amenable to recanalization, as assessed during the index procedure, using a SOFIA Flow 88 Aspiration Catheter (e.g., an extracranial carotid lesion prevents access, evidence of carotid dissection)
• •5. Clinical symptoms or non-invasive imaging suggestive of or confirming bilateral stroke or stroke in multiple territories defined as multiple large vessel occlusions (e.g., bilateral proximal MCA occlusions)
• •6. Comorbid illness that would confound the neurological or functional evaluation or is severe enough (e.g., metastatic cancer, severe congestive heart failure) such that life expectancy is \<1 year or the 90-day outcome is likely to be determined by the comorbid illness
• •7. Any contraindication to endovascular thrombectomy, such as a known history of severe contrast allergy or absolute contraindication to iodinated contrast
• •8. Participation in another clinical trial involving an investigational mechanical device (subjects may be co-enrolled in a registry study where there is no investigational treatment).