Patient-Reported Symptom Care Versus Usual Care After Esophageal Cancer Surgery: A Single-Center Phase 3 Randomized Trial

Exclusion Criteria

• •1. Human immunodeficiency virus (HIV) infection.
• •2. Psychiatric disorder.
• •3. Any other malignancy within the past 5 years (except completely cured carcinoma in situ of the cervix or basal cell/squamous cell carcinoma of the skin).
• •4. Patient ultimately did not undergo curative (radical) surgical resection.
• •5. Any unstable systemic disease (including active, uncontrolled gastrointestinal ulcer; active infection; grade 4 hypertension; unstable angina; congestive heart failure; unstable cerebrovascular disease; thrombotic disease; hepatic, renal, or metabolic disease; or unhealed fracture/wound as determined by the surgeon).
• •6. Difficulty in communication or inability to comply with long-term follow-up.
• •7. Any other condition deemed unsuitable by the investigator.