Evaluation of Physiological and Psychological Factors Involved in Exercise Intolerance in Patients With β-TTD

Inclusion Criteria

• •Patients aged 18 years or older
• •* Patients with transfusion-dependent β-thalassaemia (B0 or B+)
• •* Patients who have undergone blood transfusions at intervals of between 1 and 8 weeks for at least 5 years.
• •* Have given their free and informed written consent after being informed of the purpose of the study, its conduct and its risks.
• •* Be affiliated with a social security scheme.
• •* Not participating in any other interventional studies during the duration of this study
• •Control subjects must meet all of the following criteria to participate in the study:
• •Subject aged 18 years or older
• •Matched in age and gender to a βTTD patient included in the study.
• •Declaring to be free of known acute or chronic pathologies.
• •Have given their free written consent after being informed of the purpose of the study, its conduct and its risks.
• •Be affiliated with a social security scheme.
• •Not participate in any other interventional study during the duration of this study.
• •Have 'low' or 'moderate' IPAQ results (inactive or slightly active).