A diagnosis of PV, ET, prePMF, overt PMF or MPN-U according to 2016 WHO criteria

Characterization of the MPN driver mutation performed at any moment before enrolment

A peripheral blood (PB) sample collected at the enrolment visit suitable for plasma extraction and functional evaluation of anti-cytokine auto-Abs

Autoantibodies Against Type I Interferon in Patients Affected With Ph-negative Myeloproliferative Neoplasms (MPN-IFN Study)