Clareo Health | Integrating Metabolism, Connectivity, and Mesoscale Imaging at Ultra-high Field to Decipher Mechanisms of Resilience and Neurodegeneration in Neurological Diseases and Healthy Aging
Integrating Metabolism, Connectivity, and Mesoscale Imaging at Ultra-high Field to Decipher Mechanisms of Resilience and Neurodegeneration in Neurological Diseases and Healthy Aging
Health Status: No uncontrolled general diseases, such as cancer, autoimmune diseases, liver failure, severe or untreated high blood pressure, or severe rhythm disorders. No chronic psychiatric illnesses, including severe dementia.
MRI Compatibility: No contraindications for MRI exams (e.g., claustrophobia, metal foreign bodies, pacemakers, severe kidney failure).
Social Security Coverage: Participants must have social security coverage.
Informed Consent: The participant must have read, understood, and signed the informed consent after being adequately informed about the study.
You may not be if
Pregnancy: Pregnant women are excluded from the study.
Inability to Provide Informed Consent:
Any participant who refuses to sign the informed consent or is unable to do so due to mental or physical conditions.
Refusal of MRI: Individuals who refuse to undergo brain MRI.
Contraindications for MRI:Participants with contraindications for MRI exams, such as claustrophobia, metal foreign bodies, pacemakers, or severe kidney failure.
Medical Conditions: Known allergy to Dotarem (contrast agent) for neuroinflammatory patients. Individuals with severe renal insufficiency or other conditions that prevent MRI scanning.
Cognitive or Psychiatric Issues:
Chronic psychiatric conditions, including severe dementia or cognitive dysfunction that could hinder participation.
Legal or Institutional Restrictions:
Adults under legal protection (e.g., under guardianship or curatorship). Individuals deprived of their liberty.
Other Medical Conditions:
Individuals with neurological diseases such as ischemic accidents, brain trauma, or encephalitis.
Patients on treatments that would interfere with the study, as outlined for each disease.
Allergy to Contrast Agent:
Allergy to Dotarem for neuroinflammatory patients (MS, NMOSD, etc.).
Inability to Adhere to Protocol:
Participants who are unable or unwilling to comply with the study protocol.
