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Evaluation of the Antibacterial Effect of Ozonated Olive Oil, Propolis, and Chlorhexidine Mouthwashes in Pediatric Patients: A Randomized Controlled Clinical Trial
Streptococcus mutans and Lactobacillus acidophilus are the most common cariogenic microorganisms. Chlorhexidine has been the most widely used antibacterial mouthwash in dentistry. On the other hand, few studies have reported the antibacterial potential of Propolis and Ozonated olive oil as antibacterial agents that can be used as alternatives to Chlorhexidine. This study aims to evaluate and compare the antibacterial effect of Ozonated olive oil, Propolis, and Chlorhexidine on S. mutans and L. acidophilus count in pediatric patients.
Age
8 - 12 years
Sex
ALL
Healthy Volunteers
No
Outpatient Clinic of Pediatric dentistry, Faculty of dentistry, Alexandria University, Egypt
Alexandria, Egypt
Start Date
February 25, 2025
Primary Completion Date
May 10, 2025
Completion Date
May 10, 2025
Last Updated
September 29, 2025
51
ACTUAL participants
Ozonated olive oil
OTHER
Propolis
OTHER
Chlorhexidine
OTHER
Lead Sponsor
Alexandria University
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and ConditionsNCT06734325