To Collect Enriched Human Serum Following Hydrolyzed Collagen Intake

Exclusion Criteria

• •Relevant history or presence of any severe medical disorder, potentially interfering with this study (e.g. mal absorption, chronic gastro-intestinal diseases, heavy depression, diabetes, significant CVD events, acute cancers within last 3 years except basal cell carcinoma of the skin, etc.)
• •Significant changes in lifestyle or medication (within last 3 mo.) or surgical intervention or surgical procedure such as bariatric surgery
• •Application of corticoids (intravenously, orally or intraarticularly) and other immune-suppressing drug (within last 2 weeks)
• •Blood donation within 1 month prior to study start or during study
• •Low haemoglobin levels \< 12 g/dL
• •Regular intake of drugs or supplements possibly interfering with this study within 2 weeks prior to study start or during study (stable medication since \> 3 months e.g. L-Thyroxin, blood pressure medication etc. allowed)
• •Chronic intake of substances affecting blood coagulation (e.g. acetylic acid, anticoagulants (e.g. Marcumar), diuretics, thiazides), which in the investigator's opinion would impact participant safety
• •Not willing to avoid intake of pain relievers e.g. Paracetamol or Ibuprofen 24h prior to study days
• •Participants with history of drug, alcohol or other substance abuse, or other factors limiting their ability to co-operate during the study
• •History of hypersensitivity to fish
• •HIV-infection, acute or chronic hepatitis B and C infection
• •Known pregnancy, breast feeding or intention to become pregnant during the study. A pregnancy test will be conducted during screening and visits 1-5.
• •Participation in another clinical study within the last 4 weeks and concurrent participation in another clinical study
• •Anticipating any planned changes in lifestyle for the duration of the study
• •Participants considered inappropriate for the study by investigators, including participants who are unable or unwilling to show compliance with the protocol