Age

40–95

Sex

MALE

Healthy volunteers

Not accepted

Male patients 40-95 years of age with biopsy-confirmed localized prostate cancer.
Grade Group ≥2 (Gleason score 3+4 or higher).
Unifocal disease visible on mpMRI.
Patients undergoing HIFU as part of their standard of care
PSA \<20 ng/mL.
No metastatic disease on PSMA PET/CT
Willingness to comply with follow-up protocols (PSA testing, imaging, biopsies).

PRISM Study: Prostate Recurrence Detection Using Imaging With PSMA PET/MRI Post-high Intensity Focused Ultrasound