Impact of Infusion Line Change Frequency on Infectious Complications Related to Central Venous Catheters in the ICU - A Randomized Controlled Trial

Exclusion Criteria

• •Patient with a documented bloodstream infection at the time of inclusion
• •Patient whose central venous catheter has been in place for more than 72 hours
• •Patient with suspected catheter-related infection
• •Patient whose study catheter was inserted using a guidewire exchange
• •Patient previously enrolled in the study during the same ICU stay
• •Patient whose condition, according to the clinician, does not allow safe placement of a central venous catheter, such as:
• •* Allergy to catheter material
• •* Confirmed deep vein thrombosis at the time of insertion
• •* Inflammatory skin disorder at the insertion site
• •Patient admitted for extensive burns
• •Inadequate understanding of the French language
• •Pregnant, breastfeeding, or postpartum woman
• •Person deprived of liberty by judicial or administrative decision
• •Person receiving involuntary psychiatric care
• •Person under legal guardianship or other legal protection measure