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Pilot Study of Line-Field Confocal Optical Coherence Tomography for Detection of Mohs Micrographic Surgery Margins of Basal Cell Carcinomas | Clinical Trials | Clareo Health

RECRUITINGNA

Pilot Study of Line-Field Confocal Optical Coherence Tomography for Detection of Mohs Micrographic Surgery Margins of Basal Cell Carcinomas

NCT07182240•Roswell Park Cancer Institute

View on ClinicalTrials.gov

Summary

To assess the feasibility and provide information on the utility of noninvasive line field confocal optical coherence tomography (LC-OCT) for the presurgical assessment of Mohs micrographic surgery sites in patients undergoing removal of cutaneous basal cell carcinomas (BCC).

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Age ≥ 18 years
•Participant must understand the investigational nature of this study and provide written consent prior to receiving any study-related procedure.
•Participant must be clinically eligible for Mohs surgery as determined by their referring dermatologist and the Mohs surgeon.
•The participant must have a BCC with superficial histology or a BCC with multiple histological features that also include superficial histology, which is appropriate for Mohs surgery.

Exclusion Criteria

•Known or reported allergy to mineral oil, the optical agent used during imaging.
•Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements.
•. Any condition which in the investigator's opinion deems the subject an unsuitable candidate to undergo imaging procedure.
•Unwilling or unable to follow protocol requirements

Locations (1)

Roswell Park Comprehensive Cancer Center

Buffalo, New York, United States

Key Dates

Start Date

December 22, 2025

Primary Completion Date

December 22, 2026

Completion Date

December 22, 2026

Last Updated

February 4, 2026

Enrollment

ESTIMATED participants

Conditions

Basal Cell Carcinoma

Interventions

LC-OCT Imaging

DEVICE

Contacts

Ask RPCI

CONTACT

1-800-767-9355 askrpc@Roswellpark.org

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 4, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Pilot Study of Line-Field Confocal Optical Coherence Tomography for Detection of Mohs Micrographic Surgery Margins of Basal Cell Carcinomas

Inclusion Criteria

Exclusion Criteria

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