Histologically-confirmed diagnosis of LBCL (i.e., DLBCL, HGBCL, unclassifiable B-cell lymphoma with features intermediate between DLBCL and BL), or aggressive B-cell lymphomas with blastoid morphology (excluding blastoid variant of mantle cell lymphoma and lymphoblastic lymphoma)

Histopathological diagnosis performed between 2000 and 2019.

HIV sero-negativity

Age ≥18

Treatment with R-CHOP or other intensified polychemotherapy regimen

Availability of adequate histopathological samples at diagnosis for FISH analysis

Availability of clinical records and outcomes data

Molecular Characterization and Outcomes of Aggressive B-Cell Lymphomas.

What this study is about