Clareo Health | Sequential Imaging of Suspicion of Prostate Cancer Reducing Overdiagnosis and Unnecessary Biopsy With Timely Diagnosis of Significant Cancer
Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
St. Antonius Hospital
Age
18–any
Sex
MALE
Healthy volunteers
Not accepted
You may be eligible if
Life expectancy \> 10 years
initial PSA \< 20 ng/ml
No signs of extracapsular disease on digital rectal examination
Intermediate-risk category for suspicion of prostate cancer determined by MRI results and PSA density (PSAD): PI-RADS 3 or PI-RADS 4 with PSAD =\< 0.15
Mentally competent and able to comprehend the potential benefits and burdens of the study
Willing to undergo the follow-up protocol for a maximum of four years
written and signed informed consent
You may not be if
Men who have previously undergone a prostate biopsy
Men who have a prior PCa diagnosis
using any (anti-)hormonal therapy, including 5-alpha-reductase inhibitors
Proven germline mutation for PCa (for example: BRCA1; BRCA2)
Secondary malignancy, besides basal cell carcinoma of the skin, for which the potential participant is receiving active treatment at the time of inclusion.
severe claustrofobia or other conditions that make (repeat) MRI unsuitable (e.g., metal implants, pacemakers)
