Methylprednisolone for Moderate to Severe Traumatic Brain Injury

Exclusion Criteria

• •Known hypersensitivity to corticosteroids or any contraindication to their use.
• •History of diabetes mellitus, or capillary blood glucose \<2.8 mmol/L or \>22.2 mmol/L.
• •Shock at admission (systolic blood pressure \<90 mmHg for more than 30 minutes).
• •Pregnant or lactating women.
• •Participation in another clinical trial within the past 3 months.
• •Any condition that, in the investigator's opinion, renders the patient unsuitable for this study.