Etienne-Marie JUTANT, MD-PhD

CONTACT

Lead Sponsor

Poitiers University Hospital

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•Consent signed by the participant
•Age ≥ 18 years
•Free subject, under no legal protection
•Good understanding of the French language, allowing to answer the questionnaires
•Incident patients with pre-capillary PH confirmed by cardiac catheterization (PAPm \> 20mmHg, PCP ≤ 15 mmHg, RVP \> 2UW) having had the right diagnostic cardiac catheterization within one year (≤1 year) :
•* Cases: Patients with PAH without associated pathology: idiopathic or heritable, or with features of venous/capillary involvement, according to the clinical classification of PH
•* Controls: Patients with chronic thromboembolic PH (CTE-PTH, class 4), according to the clinical classification of PH.

•Patients classified as HTP groups 2, 3 or 5
•Patients with a diagnosis of PAH associated with a connective tissue disease, HIV, portal hypertension, congenital heart disease, bilharzia, or a drug or toxic cause considered certain according to the international classification (Aminorex, Benfluorex, Carfilzomib, Dasatinib, Dexfenfluramine, Fenfluramine, Methamphetamines, Mitomycin C, adulterated rapeseed oil)
•Patients with signs of right heart failure requiring amines and/or intensive care hospitalization at time of visit (may be included at a later visit)
•Patients refusing hair sampling or having no hair \> 2 cm to allow sampling
•Patients benefiting from enhanced protection, i.e. minors, persons deprived of their liberty by a judicial or administrative decision, persons staying in a health or social establishment, adults under legal protection, and patients in emergency situations

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