A Phase 1/2a, First-in-human, Study of BMS-986517 in Participants With Advanced Solid Tumors

You may be eligible if

• Participants must have an ECOG performance status of 0 to 1.
• Participants must have measurable disease by RECIST v1.1 (radiologically measured by the Investigator).
• Participants must have documented histologically or cytologically confirmed advanced, unresectable/metastatic solid tumors, including NSCLC, HNSCC, TNBC, and HR+/HER2- breast cancer.
• Participants must not have concurrent malignancy (present during Screening) requiring treatment or history of prior malignancy active within 2 years prior to treatment assignment.
• Participants must not have history of serious recurrent infections.
• Participants must not have impaired cardiac function or history of severe heart disease.
• For participants in Part 1B and 2B: Active autoimmune disease or requirement for systemic immunosuppressive therapy.
• For participants in Part 1B and 2B: History of interstitial lung disease (ILD) or pneumonitis requiring systemic steroids, or current/suspected ILD/pneumonitis.
• For participants in Part 1B and 2B: Significant risk of hemorrhage, including tumor invasion of major vessels or recent clinically significant bleeding.