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COMPLETEDNCT07152301

Inflammation, Epigenetics in CHF Patients With AF

the goal of this case-control cross-sectional study is assessing in a cohort of patients with CHF and permanent AF * The serum levels of some candidate cytokine variables and their relationship with ...

Lead sponsor: University of Palermo•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

University of Palermo

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•≥18 years
•Left ventricular ejection fraction \>40%
•New York Heart Association class II-IV symptoms
•NT-proBNP ≥600 pg/mL, or ≥900 pg/mL if AF was present on baseline electrocardiography

Exclusion Criteria

•\- Other AF subtypes (paroxysmal, persistent, long-standing persistent)
•At least one of the following criteria:
•Acute heart failure
•NYHA IV
•NT-proBNP \>4000 pg/mL
•Significant valvular disease
•Mechanical prosthesis
•Cardiovascular implantable devices
•Active malignancy
•Inflammatory or infectious diseases
•Severe renal (eGFR \<30 mL/min/m²) or hepatic failure
•Chronic steroid/anti-inflammatory therapy

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: September 4, 2025Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment164

Start dateJan 2020

Last updatedSep 4, 2025

Condition

Congestive Heart Failure Chronic Atrial Fibrillation (Permanent)

Locations shown

Internal Medicine and Stroke Care Ward, Policlinic Hospital of Palermo, Sicily

Palermo, PA

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 4, 2025Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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