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Assessing Human Phosphate Tolerance and Its Dependency on Age and Sex
Kidney function declines with age and this could affect phosphate balance after an acute phosphate load (increased phosphate intake). In daily life, we regularly experience acute phosphate loads through our diet. The aim of this clinical study is to determine whether the body's response to increased phosphate intake changes with age and whether there are sex differences in this response.
Forty subjects (males and females aged 18-25 or 63-70) will ingest an oral phosphate load, after which their body's response will be assessed by collecting blood and urine samples over a period of ten hours.
Age
25 - 70 years
Sex
ALL
Healthy Volunteers
Yes
Start Date
September 30, 2025
Primary Completion Date
September 30, 2026
Completion Date
September 1, 2027
Last Updated
September 2, 2025
40
ESTIMATED participants
Oral phosphate load
OTHER
Lead Sponsor
University of Zurich
NCT07241390
NCT04634916
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