1. Adults of both genders aged 18 or older at the time of study inclusion.
2. Patients with medical records from the selected sites between 2016 and 2023 with at least one year of follow-up records.
3. Patients receiving routine treatment in the participating sites.
4. Patients with an SLE diagnosis.
5. Due to the retrospective nature of the study a waiver grant of the consent will be requested from the IRB/IEC for the study participants, if waiver not granted Patient or next of kin/legal representative (for deceased patients at study entry) willing and able to provide written informed consent according to the local regulations.
You may not be if
1. Patients with new-onset SLE as they will have insufficient data.
2. Patients whose records have insufficient data (for example, due to lost follow up).