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COMPLETEDNANCT07143370

Microbial Colonization in Three Dimensional (3D) Printed Orthodontic Clear Aligners

This study is being done to compare conventional clear aligners with 3D printed clear aligners to assess if there is any significant difference between the microbial colonization of these appliances. ...

Lead sponsor: University of Michigan•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

University of Michigan

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Participants are in the permanent dentition
•Participants can understand written English instructions
•Participants have no history of smoking
•Participants will not undergo any active orthodontic treatment.

Exclusion Criteria

•Periodontal disease/gingivitis or craniofacial anomalies.
•Severe tooth crowding

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: November 6, 2025Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment30

Start dateSep 2025

Last updatedNov 6, 2025

Condition

Orthodontic Aligner Microbial Colonization

Locations shown

University of Michigan

Ann Arbor, Michigan

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: November 6, 2025Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions