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Noninvasive Ventilation Weaning Protocol in COPD

NCT07133711·1 site·ClinicalTrials.gov

What this study is about

Take this into the appointment.

Saves the questions and what to expect into your notes, next to the visit they belong to.

Keep this study

Lead

Assiut University

A study to compare protocolized weaning from non-invasive ventilation using three potential strategies of weaning from NIV * Stepwise reduction of duration of NIV use, * Stepwise reduction in pressure support of NIV, and * Immediate withdrawal of NIV. Among patients with Acute respiratory failure due to acute exacerbation of COPD.

Age

18–80

Sex

ALL

Healthy volunteers

Not accepted

You may be eligible if

All COPD patients admitted in the respiratory ICU with acute Hypercapnic Respiratory Failure who will be managed with Noninvasive Ventilation without the need for invasive mechanical ventilation will be eligible for inclusion in the study.

You may not be if

Age: less than 18 years,
End organ failure as cardiac/ Liver/ Renal,
Patients on home NIV and
Those who required NIV for respiratory failure due to diseases other than COPD were not considered for the study.

The record

StatusCompleted

PhaseNo phase

Taking part60

StartedAug 2023

UpdatedAug 21, 2025

Conditions

Chronic Obstructive Pulmonary Disease

Where1

Assiut University hospital
Asyut, Egypt

Clareo Health | Noninvasive Ventilation Weaning Protocol in COPD