Loading clinical trials...

Study of Efficacy and Safety of Cream Infused With HuangQin (Root of Scutellaria Baicalensis) Extract for the Reduction of Hyperpigmentation | Clinical Trials | Clareo Health

COMPLETEDNA

Study of Efficacy and Safety of Cream Infused With HuangQin (Root of Scutellaria Baicalensis) Extract for the Reduction of Hyperpigmentation

NCT07133204•Mae Fah Luang University

View on ClinicalTrials.gov

Summary

The aim of this study is to evaluate the efficacy of a topical cream infused with Scutellaria baicalensis extract in reducing hyperpigmentation on the face. The study is experimental clinical pilot study as a single group pretest-posttest. A ROAT is conducted 1 week prior to the experiment. Participant apply the cream on the hypigmented area daily. Facial skin parameters (i.e. melanin index, erythema index) is evaluated at week 0, 1, 2 and 4.

Eligibility

Age

30 - 60 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Male or Female
•Has at least 1 hyperpigmentation spot (size \> 3mm) on either side of the face
•30-60 y/o
•Fitzpatrick skin types II-IV
•Agrees to use sunscreen SPF50+ and willing to avoid strong sunlight exposure during the study

Exclusion Criteria

•Pregnant or lactating
•Use of whitening products or treatment within 1 month before this study
•Currently using contraceptives
•History of allergy to any ingredient in the intervention cream
•Has skin conditions which can interfere with the measurement (i.e. severe acne, eczema, herpes simplex)
•Severe disease (i.e. immunodeficiency, cancer)
•Enrolled in other clinical study within 3 month before this study

Locations (1)

Mae Fah Luang University

Muang, Changwat Chiang Rai, Thailand

Key Dates

Start Date

April 1, 2025

Primary Completion Date

June 30, 2025

Completion Date

July 20, 2025

Last Updated

August 20, 2025

Enrollment

ACTUAL participants

Conditions

Hyperpigmentation; Melanin

Interventions

Investigator developed cream infused with HuangQin extract

OTHER