The Impact of GLP Medication on Colonoscopy Bowel Preparation Quality

Exclusion Criteria

• •Unable to provide informed consent, e.g., dementia
• •Patient refuses the USMSTF recommended bowel cleansing regimen for patients with diabetes or obesity (split-dose 4 liters polyethylene glycol + 15 mg bisacodyl the afternoon before; low residue diet 3 days before colonoscopy; clear liquid diet the day before colonoscopy)
• •Risk factors for inadequate bowel preparation besides diabetes and obesity with a likelihood ratio of 1.6 or greater:
• •1. Cirrhosis
• •2. Parkinson's disease
• •3. Dementia
• •4. Tricyclic antidepressant use
• •5. Opioid use
• •6. Gastroparesis\* or suspected gastric outlet obstruction on pre-procedure imaging (\*defined based on a documented 4-hour solid phase gastric emptying study or prior history of retained gastric contents during upper endoscopy)
• •7. Previous colorectal surgery
• •8. Prior history of inadequate bowel preparation